Computational Structural Biology in Thrombosis and Haemostasis

Gianluca Interlandi

Foege N430E gianluca_at_uw_dot_edu

My laboratory combines tools from computational structural biology, like molecular dynamics simulations and Monte Carlo methods, with biochemical and biophysical assays to unravel the molecular basis behind biological processes like the blood coagulation cascade and cellular adhesion.

You can find a list of publications here.

Examples of projects in my laboratory include:

1) The function of von Willebrand Factor.

2) Polymerization of fibrin molecules.

3) Allostery in cellular adhesion.

4) Orientation of protein molecules on material surfaces.

Lab members:
Eric Pederson graduate student

Past lab members:
Kalkena Sivanesam postdoctoral fellow (2017-2018)
Elisa Harrison graduate student (in collaboration with Dr. David Castner) (2013-2017)
Zachary Jacobi rotation graduate student (Fall 2015)
Yiming Li undergraduate capstone student (2016-2018)
Rachel Tsai undergraduate student biochemistry (2015-2017)
Nichole Tyler research scientist (2014-2015)